Cytotoxic Activity of Pinang Fruit Leather (Areca Catechu) and Cinnamon Leaf Ethanol Extract

Abstract

The areca plant (Areca cathecu) and cinnamon (Cinnamomum burmannii) have
anticancer properties. The aim of this research is to know the cytotoxic effect of Areca catechu
of ethanol extract on T47D breast cancer cell culture and Cinnamomum burmannii leaves of
ethanol extract on WiDr colon cancer cell culture.
The obtained simplicia macerated to obtain ethanol extract of pinang peel and cinnamon
leaves. The method used in testing cytotoxic activity was MTT (3- [4,5-dimethylthiazol-2yl] -2, 5-
diphenyltetrazolium bromide) to obtain IC50 values.
The results showed that ethanol extract of pinang peel and cinnamon leaf did not have
cytotoxic effect on T47D culture with IC50 467,34 μg/mL and on WiDr culture with IC50 405,69
μg/ml.