Antibacterial Activity of Suruhan Leaf Extract (Peperomia pellucida L. Kunth) against Klebsiella pneumoniae

Abstract

Klebsiella pneumoniae is one of the pathogens which are gram negative bacteria and
that causes pneumonia. Treatment of Klebsiella pneumoniae bacterial infection is performed
through the use of antibiotics. The phenomenon of resistance has encouraged the search for
natura-based antimicrobials where one of the plants with antibacterial potency is suruhan
(Peperomia pellucida L. Kunth).
The purpose of this study was to determine the antibacterial activity, the value of the
Minimum Inhibitory Concentration (MIC) and the Minimum Killer Concentration (KBM) from the
leaf extract of suruhan leaves on Klebsiella pneumoniae using a liquid dilution method. The
extraction method used in this study was maceration. The extract obtained tested with a
concentration of 100%; 50%; 25%; 12.5%; 6.25%; 3.125%; 1.562%; 0.781%; 0.391% and
0.195% (v / v).
The results showed that leaf extract had antibacterial activity against Klebsiella
pneumoniae with a KBM value of 25%.